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Book

Impaired Bilirubin Conjugation

Neeraj Ramakrishnan  1 , Khaled Bittar  2 , Ishwarlal Jialal  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
.
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Book

Impaired Bilirubin Conjugation

Neeraj Ramakrishnan et al.
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Excerpt

Bilirubin circulates in the conjugated and unconjugated forms (predominant). Disorders of impaired bilirubin conjugation classically present with elevated levels of unconjugated or indirect bilirubin. Major causes of impaired conjugation of bilirubin include inherited disorders and secondary causes such as drugs. Disorders can range from an asymptomatic presentation to a very severe bilirubin encephalopathy (kernicterus). In this review, we focus on the inherited disorders and their management.

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Conflict of interest statement

Disclosure: Neeraj Ramakrishnan declares no relevant financial relationships with ineligible companies.

Disclosure: Khaled Bittar declares no relevant financial relationships with ineligible companies.

Disclosure: Ishwarlal Jialal declares no relevant financial relationships with ineligible companies.

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References

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