Primary hepatoid adenocarcinoma of the orbit

Joseph B Alsberge; F Lawson Grumbine; Michele M Bloomer; M Reza Vagefi; Robert C Kersten

doi:10.1016/j.ajoc.2016.10.006

Primary hepatoid adenocarcinoma of the orbit

Am J Ophthalmol Case Rep. 2016 Oct 25:5:38-40. doi: 10.1016/j.ajoc.2016.10.006. eCollection 2017 Apr.

Authors

Joseph B Alsberge¹, F Lawson Grumbine¹, Michele M Bloomer¹, M Reza Vagefi¹, Robert C Kersten¹

Affiliation

¹ Department of Ophthalmology, University of California, San Francisco, USA.

Abstract

Purpose: To report a case of primary hepatoid adenocarcinoma of the orbit.

Observations: An adult patient was referred for evaluation of an orbital mass. Histopathology of the orbital biopsy indicated a carcinoma with hepatoid features. Laboratory studies revealed normal liver function tests, elevated serum alpha-fetoprotein, and whole-body positron emission tomography/computed tomography scan showed no evidence of liver involvement or an alternative primary origin.

Conclusions and importance: To the authors' knowledge, this is the first reported case of primary hepatoid adenocarcinoma of the orbit.

Keywords: Alpha-fetoprotein; Hepatoid adenocarcinoma; Orbital tumor.

Publication types

Case Reports