Theophylline as a precision therapy in a young girl with PIK3R1 immunodeficiency

J Allergy Clin Immunol Pract. 2018 Nov-Dec;6(6):2165-2167. doi: 10.1016/j.jaip.2018.02.029. Epub 2018 Mar 3.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Class Ia Phosphatidylinositol 3-Kinase
  • Female
  • Humans
  • Immunity / drug effects
  • Immunologic Deficiency Syndromes / drug therapy*
  • Infections
  • Lymphoproliferative Disorders
  • Mutation / genetics*
  • Phenotype
  • Phosphatidylinositol 3-Kinases / genetics*
  • Phosphodiesterase Inhibitors / therapeutic use*
  • Precision Medicine / methods*
  • Theophylline / therapeutic use*
  • Treatment Outcome

Substances

  • Phosphodiesterase Inhibitors
  • Theophylline
  • PIK3R1 protein, human
  • Class Ia Phosphatidylinositol 3-Kinase