Transplantation and Alternatives to Treat Autoimmune Diseases

Adv Exp Med Biol. 2018:1089:59-72. doi: 10.1007/5584_2018_177.


Transplantation is considered as one of the methods for the treatment of autoimmune diseases. There are different sorts of transplantation which improved the situation for the cure of different kinds of autoimmune diseases. Cord blood transplantation is favored over other transplant techniques. The propelled treatments incorporate interferon administrative elements and mesenchymal stromal cells for the management of immune system issue particularly in the treatment of rheumatoid joint inflammation. According to the studies conducted, it was proven that cord blood/UC mesenchymal cells along with DMARDs, without consistent organization expanded the level of administrative regulatory T-cells of the peripheral blood which might be a protected and huge technique for the treatment of patients experiencing rheumatoid joint inflammation. This review article focusses on different organ transplantation and alternative methods to treat autoimmune condition like rheumatoid arthritis. Using 3D printing and artificial intelligence are some of the recent trends that may be used for the management of autoimmune diseases.

Keywords: Mesenchymal stromal cells; Rheumatoid arthritis; Stem cells; Transplantation.

Publication types

  • Review

MeSH terms

  • Arthritis, Rheumatoid / therapy
  • Autoimmune Diseases / therapy*
  • Bone Marrow Transplantation*
  • Humans
  • Mesenchymal Stem Cell Transplantation*
  • Mesenchymal Stem Cells / cytology