Combination of common and novel rare NUDT15 variants improves predictive sensitivity of thiopurine-induced leukopenia in children with acute lymphoblastic leukemia

Haematologica. 2018 Jul;103(7):e293-e295. doi: 10.3324/haematol.2018.187658. Epub 2018 Mar 8.

¹ Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
² Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
³ Department of Pharmaceutical Sciences and Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
⁴ Department of Thoracic Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
⁵ Department of Precision Medicine, China-Japan Friendship Hospital, Beijing, China.
⁶ State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
⁷ Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Xiangya Hospital, Central South University, Changsha, China.
⁸ Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China xuheng81916@scu.edu.cn gaoju651220@126.com shuyang1986@gmail.com.
⁹ Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China xuheng81916@scu.edu.cn gaoju651220@126.com shuyang1986@gmail.com.

No abstract available

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