Imaging Evaluation Following 90Y Radioembolization of Liver Tumors: What Radiologists Should Know

Korean J Radiol. 2018 Mar-Apr;19(2):209-222. doi: 10.3348/kjr.2018.19.2.209. Epub 2018 Feb 22.


Radioembolization using beta-emitting yttrium-90 microspheres is being increasingly used for the treatment of primary and metastatic liver cancers. It is a form of intra-arterial brachytherapy which delivers intense radiation to liver tumors with little embolic effect; this mode of action results in unique post-treatment imaging findings. It is important to understand these imaging findings to avoid misinterpretation of tumor response and to determine further management of the disease. Herein, we discuss the current concepts for assessing tumor response, common post-treatment imaging features, and associated complications following radioembolization.

Keywords: Liver cancer; Post-treatment imaging; Radioembolization; Selective internal radiation therapy; Yttrium-90.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / blood
  • Brachytherapy
  • Embolization, Therapeutic*
  • Humans
  • Liver / diagnostic imaging
  • Liver Neoplasms / therapy*
  • Positron-Emission Tomography
  • Radiopharmaceuticals / chemistry
  • Treatment Outcome
  • Yttrium Radioisotopes / chemistry


  • Biomarkers, Tumor
  • Radiopharmaceuticals
  • Yttrium Radioisotopes
  • Yttrium-90