The role of FDG-PET/CT in gynecologic imaging: an updated guide to interpretation and challenges

Abdom Radiol (NY). 2018 Sep;43(9):2474-2486. doi: 10.1007/s00261-017-1441-8.

Abstract

All women, during their lifetime, are at risk of developing some form of gynecologic malignancy. The role of FDG-PET/CT has become more established in the management of gynecologic malignancies in the last decade. In this article, we will review the role of FDG-PET/CT in endometrial, cervical, ovarian, and vaginal cancer, by highlighting its strengths and limitations. While the role in initial or pre-operative staging for FDG-PET/CT is controversial, it allows noninvasive detection of equivocal or distant metastases, may alter stage and prognosis, and can guide or help eliminate unnecessary interventions that may not be beneficial. FDG-PET/CT is a useful adjunct to traditional staging with MR and CT.

Keywords: FDG-PET/CT; Gynecologic imaging; Gynecologic malignancies.

Publication types

  • Review

MeSH terms

  • Female
  • Fluorodeoxyglucose F18
  • Genital Diseases, Female / diagnostic imaging*
  • Genital Diseases, Female / pathology
  • Humans
  • Neoplasm Staging
  • Positron Emission Tomography Computed Tomography*
  • Radiopharmaceuticals

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18