Clinical use of cardiac PET/MRI: current state-of-the-art and potential future applications

Jpn J Radiol. 2018 May;36(5):313-323. doi: 10.1007/s11604-018-0727-2. Epub 2018 Mar 10.


Combined PET/MRI is a novel imaging method integrating the advances of functional and morphological MR imaging with PET applications that include assessment of myocardial viability, perfusion, metabolism of inflammatory tissue and tumors, as well as amyloid deposition imaging. As such, PET/MRI is a promising tool to detect and characterize ischemic and non-ischemic cardiomyopathies. To date, the greatest benefit may be expected for diagnostic evaluation of systemic diseases and cardiac masses that remain unclear in cardiac MRI, as well as for clinical and scientific studies in the setting of ischemic cardiomyopathies. Diagnosis and therapeutic monitoring of cardiac sarcoidosis has the potential of a possible 'killer-application' for combined cardiac PET/MRI. In this article, we review the current evidence and discuss current and potential future applications of cardiac PET/MRI.

Keywords: Cardiac tumor; Inflammatory heart disease; Ischemic cardiomyopathy; Non-ischemic cardiomyopathy; Rheumatic heart disease.

Publication types

  • Review

MeSH terms

  • Heart / diagnostic imaging
  • Heart Diseases / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / trends
  • Multimodal Imaging / methods*
  • Multimodal Imaging / trends
  • Positron-Emission Tomography / methods*
  • Positron-Emission Tomography / trends