A History of Left Atrial Appendage Occlusion

Interv Cardiol Clin. 2018 Apr;7(2):143-150. doi: 10.1016/j.iccl.2017.12.005.


A new era in antiembolic therapy has been initiated by the growing numbers of device-based therapies. Early concerns surrounding eliminating this enigmatic structure have not proven true. Other benefits are being further evaluated. Many other questions remain, such as whether there is a device-specific outcome effect or whether it is a class effect. Other questions include other devices, what head-to-head studies will show, and the impact of residual leak. Left atrial appendage using the Watchman ablation strategy can reduce cardioembolic stroke, with comparable or fewer adverse effects by device technology than obtained by long-term anticoagulation with its attendant bleeding risks.

Keywords: Antiembolic therapy; Atrial fibrillation; Left atrial appendage; Watchman ablation strategy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anticoagulants / administration & dosage
  • Anticoagulants / therapeutic use
  • Atrial Appendage / surgery*
  • Atrial Fibrillation / complications*
  • Atrial Fibrillation / therapy
  • Catheter Ablation / methods
  • Female
  • Humans
  • Middle Aged
  • Prosthesis Design
  • Prosthesis Implantation / instrumentation*
  • Rheumatic Heart Disease / complications
  • Rheumatic Heart Disease / diagnosis*
  • Stroke / prevention & control*
  • Thrombosis / diagnosis
  • Thrombosis / pathology
  • Thrombosis / surgery
  • Treatment Outcome


  • Anticoagulants