Treatment options for Primary CNS Lymphoma

J Pak Med Assoc. 2018 Mar;68(3):499-500.


Primary CNS lymphoma (PCNSL) is a rare and aggressive brain tumour that is uniformly fatal. The rarity of the disease and the poor response to treatment makes it difficult to reach a consensus with regards to treatment options. In this review, the authors have discussed different treatment modalities used in the management of PCNSL including chemotherapy, surgery and radiation, as well as the results of recent clinical trials on treatment options for PCNSL.

Keywords: Primary CNS Lymphoma, Cerebral malignancy, Chemotherapy, Radiotherapy.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Brain Neoplasms / therapy*
  • Central Nervous System Neoplasms / therapy
  • Cranial Irradiation*
  • Humans
  • Lymphoma / therapy*
  • Neurosurgical Procedures
  • Radiotherapy