Phyllodes Tumor of the Prostate With Epithelial Intestinal Metaplasia

Am J Surg Pathol. 2018 Jun;42(6):836-839. doi: 10.1097/PAS.0000000000001052.

Abstract

Phyllodes tumor of the prostate is a rare mesenchymal tumor conventionally regarded as a stromal tumor of undetermined malignant potential. While the initial presentation is that of urinary obstruction and/or hematuria, the subsequent clinical behavior is thought to be a function of stromal cellularity and cytologic changes of malignancy. Of histologic interest, the epithelial component of this tumor varies, including intestinal metaplasia, as seen in the present case.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Epithelial Cells / chemistry
  • Epithelial Cells / pathology*
  • GATA3 Transcription Factor / analysis
  • Humans
  • Immunohistochemistry
  • Kallikreins / analysis
  • Male
  • Metaplasia
  • Neoplasm Grading
  • Phyllodes Tumor / chemistry
  • Phyllodes Tumor / pathology*
  • Phyllodes Tumor / surgery
  • Prostate-Specific Antigen / analysis
  • Prostatic Neoplasms / chemistry
  • Prostatic Neoplasms / pathology*
  • Prostatic Neoplasms / surgery

Substances

  • GATA3 Transcription Factor
  • GATA3 protein, human
  • KLK3 protein, human
  • Kallikreins
  • Prostate-Specific Antigen

Supplementary concepts

  • Phyllodes Tumor of the Prostate