Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May 4;360(6388):548-552.
doi: 10.1126/science.aar8380. Epub 2018 Mar 15.

Pleistocene North African Genomes Link Near Eastern and sub-Saharan African Human Populations

Affiliations

Pleistocene North African Genomes Link Near Eastern and sub-Saharan African Human Populations

Marieke van de Loosdrecht et al. Science. .

Abstract

North Africa is a key region for understanding human history, but the genetic history of its people is largely unknown. We present genomic data from seven 15,000-year-old modern humans, attributed to the Iberomaurusian culture, from Morocco. We find a genetic affinity with early Holocene Near Easterners, best represented by Levantine Natufians, suggesting a pre-agricultural connection between Africa and the Near East. We do not find evidence for gene flow from Paleolithic Europeans to Late Pleistocene North Africans. The Taforalt individuals derive one-third of their ancestry from sub-Saharan Africans, best approximated by a mixture of genetic components preserved in present-day West and East Africans. Thus, we provide direct evidence for genetic interactions between modern humans across Africa and Eurasia in the Pleistocene.

Similar articles

See all similar articles

Cited by 20 articles

  • Human auditory ossicles as an alternative optimal source of ancient DNA.
    Sirak K, Fernandes D, Cheronet O, Harney E, Mah M, Mallick S, Rohland N, Adamski N, Broomandkhoshbacht N, Callan K, Candilio F, Lawson AM, Mandl K, Oppenheimer J, Stewardson K, Zalzala F, Anders A, Bartík J, Coppa A, Dashtseveg T, Évinger S, Farkaš Z, Hajdu T, Bayarsaikhan J, McIntyre L, Moiseyev V, Okumura M, Pap I, Pietrusewsky M, Raczky P, Šefčáková A, Soficaru A, Szeniczey T, Szőke BM, Van Gerven D, Vasilyev S, Bell L, Reich D, Pinhasi R. Sirak K, et al. Genome Res. 2020 Mar;30(3):427-436. doi: 10.1101/gr.260141.119. Epub 2020 Feb 25. Genome Res. 2020. PMID: 32098773
  • The spread of steppe and Iranian-related ancestry in the islands of the western Mediterranean.
    Fernandes DM, Mittnik A, Olalde I, Lazaridis I, Cheronet O, Rohland N, Mallick S, Bernardos R, Broomandkhoshbacht N, Carlsson J, Culleton BJ, Ferry M, Gamarra B, Lari M, Mah M, Michel M, Modi A, Novak M, Oppenheimer J, Sirak KA, Stewardson K, Mandl K, Schattke C, Özdoğan KT, Lucci M, Gasperetti G, Candilio F, Salis G, Vai S, Camarós E, Calò C, Catalano G, Cueto M, Forgia V, Lozano M, Marini E, Micheletti M, Miccichè RM, Palombo MR, Ramis D, Schimmenti V, Sureda P, Teira L, Teschler-Nicola M, Kennett DJ, Lalueza-Fox C, Patterson N, Sineo L, Coppa A, Caramelli D, Pinhasi R, Reich D. Fernandes DM, et al. Nat Ecol Evol. 2020 Mar;4(3):334-345. doi: 10.1038/s41559-020-1102-0. Epub 2020 Feb 24. Nat Ecol Evol. 2020. PMID: 32094539
  • Zinc isotopes in Late Pleistocene fossil teeth from a Southeast Asian cave setting preserve paleodietary information.
    Bourgon N, Jaouen K, Bacon AM, Jochum KP, Dufour E, Duringer P, Ponche JL, Joannes-Boyau R, Boesch Q, Antoine PO, Hullot M, Weis U, Schulz-Kornas E, Trost M, Fiorillo D, Demeter F, Patole-Edoumba E, Shackelford LL, Dunn TE, Zachwieja A, Duangthongchit S, Sayavonkhamdy T, Sichanthongtip P, Sihanam D, Souksavatdy V, Hublin JJ, Tütken T. Bourgon N, et al. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4675-4681. doi: 10.1073/pnas.1911744117. Epub 2020 Feb 18. Proc Natl Acad Sci U S A. 2020. PMID: 32071235 Free PMC article.
  • Conserved novel ORFs in the mitochondrial genome of the ctenophore Beroe forskalii.
    Schultz DT, Eizenga JM, Corbett-Detig RB, Francis WR, Christianson LM, Haddock SHD. Schultz DT, et al. PeerJ. 2020 Jan 27;8:e8356. doi: 10.7717/peerj.8356. eCollection 2020. PeerJ. 2020. PMID: 32025367 Free PMC article.
  • Human Genomic Diversity Where the Mediterranean Joins the Atlantic.
    Hernández CL, Pita G, Cavadas B, López S, Sánchez-Martínez LJ, Dugoujon JM, Novelletto A, Cuesta P, Pereira L, Calderón R. Hernández CL, et al. Mol Biol Evol. 2020 Apr 1;37(4):1041-1055. doi: 10.1093/molbev/msz288. Mol Biol Evol. 2020. PMID: 31816048 Free PMC article.
See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback