Population genetics and GWAS: A primer

PLoS Biol. 2018 Mar 16;16(3):e2005485. doi: 10.1371/journal.pbio.2005485. eCollection 2018 Mar.


This primer provides some background to help non-specialists understand a new theoretical evolutionary genetics study that helps explain why thousands of variants of small effect contribute to complex traits.

Publication types

  • Comment

MeSH terms

  • Genetics, Population
  • Genome-Wide Association Study*
  • Humans
  • Phenotype
  • Polymorphism, Single Nucleotide*

Grants and funding

The author received no specific funding for this work.