HPV vaccination syndrome: A clinical mirage, or a new tragic fibromyalgia model

Abstract

Independent investigators have described the onset of a chronic painful dysautonomic syndrome soon after human papillomavirus (HPV) vaccination. The veracity of this syndrome is hotly debated. Many of the reported post-HPV vaccination cases fullfill fibromyalgia diagnostic criteria. This article discusses the arguments favoring the existence of a syndrome associated to HPV vaccination. We propose that fibromyalgia dysautonomic-neuropathic model could help in the diagnostic and therapeutic process in those patients in whom the onset of a painful chronic illness began after HPV immunization. On the other hand, if its veracity is corroborated, HPV vaccination syndrome may become a new tragic fibromyalgia model.

Keywords: Chronic fatigue syndrome; Disautonomía; Dysautonomia; Fibromialgia; Fibromyalgia; HPV vaccination syndrome; HPV vaccine; Neuropatía de fibras pequeñas; Small fiber neuropathy; Síndrome de fatiga crónica; Síndrome posvacunal de VPH; Vacuna del papiloma.