Imaging of congenital central nervous system infections

Pediatr Radiol. 2018 Apr;48(4):513-523. doi: 10.1007/s00247-018-4092-1. Epub 2018 Mar 17.


Congenital central nervous system (CNS) infections are a cause of significant morbidity and mortality. The recent Zika virus outbreak raised awareness of congenital CNS infections. Imaging can be effective in diagnosing the presence and severity of infection. In this paper we review the clinical presentations and imaging characteristics of several common and less common congenital CNS infections.

Keywords: Brain; Central nervous system; Computed tomography; Congenital; Fetus; Infant; Infection; Magnetic resonance imaging; Virus.

Publication types

  • Review

MeSH terms

  • Central Nervous System Infections / congenital*
  • Central Nervous System Infections / diagnostic imaging*
  • Cytomegalovirus Infections / diagnostic imaging
  • Diagnosis, Differential
  • HIV Infections / diagnostic imaging
  • Herpes Simplex / diagnostic imaging
  • Humans
  • Infant, Newborn
  • Toxoplasmosis / diagnostic imaging
  • Zika Virus Infection / diagnostic imaging