Substance use disorders and medical comorbidities among high-need, high-risk patients with diabetes

Drug Alcohol Depend. 2018 May 1:186:86-93. doi: 10.1016/j.drugalcdep.2018.01.008. Epub 2018 Mar 3.

Abstract

Background: The majority of the U.S. healthcare resources are utilized by a small population characterized as high-risk, high-need persons with complex care needs (e.g., adults with multiple chronic conditions). Substance use disorders (SUDs) and mental health disorders (MHDs) are a driver of poor health and additional healthcare costs, but they are understudied among high-need patients.

Objective: We examine the prevalence and correlates of SUDs and MHDs among adults with high-risk diabetes, who are patients at the top 10% risk score for developing poor outcomes (hospital admission or death).

Methods: A risk algorithm developed from Duke University Health System electronic health records (EHRs) data was used to identify patients with high-risk diabetes for targeting home-based primary care. The EHR data of the 263 patients with high-risk diabetes were analyzed to understand patterns of SUDs and MHDs to inform care-coordinating efforts.

Results: Both SUDs (any SUD 48.3%, alcohol 12.5%, tobacco 38.8%, drug 23.2%) and MHDs (any MHD 74.9%, mood 53.2%, sleep 37.3%, anxiety 32.7%, schizophrenia/psychotics/delusional 14.8%, dementia/delirium/amnestic/cognitive 14.4%, adjustment 9.1%) were prevalent. Overall, 81.7% of the sample had SUD or MHD. Elevated odds of SUD were noted among men (tobacco, alcohol) and those who were never-married (alcohol, cannabis). African-American race (vs. other race/ethnicity) was associated with lower odds of anxiety disorders.

Conclusion: While data are limited to one large academic health system, they provide clinical evidence revealing that 82% of patients with high-risk diabetes had SUD and/or MHD recorded in their EHRs, highlighting a need for developing service models to optimize high-risk care.

Keywords: Comorbidity; Diabetes mellitus; Electronic health records; Mood disorder; Sleep disorder; Substance use disorder.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Comorbidity
  • Delivery of Health Care / statistics & numerical data
  • Diabetes Complications / epidemiology*
  • Diabetes Complications / mortality
  • Female
  • Hospital Mortality
  • Humans
  • Male
  • Mental Disorders / complications
  • Mental Disorders / epidemiology
  • Middle Aged
  • Prevalence
  • Risk
  • Socioeconomic Factors
  • Substance-Related Disorders / complications*
  • Substance-Related Disorders / epidemiology
  • Substance-Related Disorders / mortality
  • Treatment Outcome