Solitary fibrous tumour/haemangiopericytoma of the spinal cord
Neurocirugia (Astur : Engl Ed). 2018 Nov-Dec;29(6):309-313.
doi: 10.1016/j.neucir.2018.01.005.
Epub 2018 Mar 17.
[Article in
English,
Spanish]
Affiliations
- 1 Servicio de Neurocirugía, Hospital Clínico Universitario de Santiago de Compostela , Santiago de Compostela, A Coruña, España. Electronic address: annaflores36@gmail.com.
- 2 Servicio de Neurocirugía, Hospital Clínico Universitario de Santiago de Compostela , Santiago de Compostela, A Coruña, España.
- 3 Servicio de Anatomía Patológica, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España.
Abstract
Solitary fibrous tumours/haemangiopericytomas (SFT/HPC) are fibroblastic mesenchymal neoplasms that harbour a genetic fusion of NAB2/STAT6. There are few reported cases in the central nervous system (CNS), of which spinal tumours are minority. We present a case of a 63-year-old woman with progressive paraparesis and a sensory level of T6. On the MRI we detected an intradural extramedullary lesion on T9-T10. We performed a laminectomy with an intraoperative ultrasound study in which we observed a heterogeneous lesion with an infiltrating pattern affecting the medulla at several points, and resection of the lesion. Immunohistological findings revealed positivity for vimentin, CD34 and STAT6; Ki-67 was 2%. A final diagnosis of SFT/HPC with SFT phenotype was made. SFT/HPC of the CNS is a rare neoplasm that should be taken into account in the differential diagnosis of these kinds of lesions, as clinical and MRI findings often lead to errors in diagnostic approach. The support of intraoperative ultrasound can assist in surgical decision-making.
Keywords:
Dorsal; Haemangiopericytoma; Hemangiopericitoma; MRI; Resonancia magnética; Solitary fibrous tumour; Spinal tumour; Thoracic; Tumor espinal; Tumor fibroso solitario.
Copyright © 2018 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.
MeSH terms
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Biomarkers, Tumor / analysis
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Decompression, Surgical
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Diagnostic Errors
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Female
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Hemangiopericytoma / chemistry
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Hemangiopericytoma / complications
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Hemangiopericytoma / diagnostic imaging
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Hemangiopericytoma / surgery*
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Humans
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Laminectomy
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Lumbar Vertebrae / surgery
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Magnetic Resonance Imaging
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Meningeal Neoplasms / diagnosis
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Meningioma / diagnosis
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Middle Aged
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Neuroimaging
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Paraplegia / etiology
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Solitary Fibrous Tumors / chemistry
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Solitary Fibrous Tumors / complications
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Solitary Fibrous Tumors / diagnostic imaging
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Solitary Fibrous Tumors / surgery*
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Somatosensory Disorders / etiology
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Spinal Cord Neoplasms / chemistry
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Spinal Cord Neoplasms / complications
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Spinal Cord Neoplasms / diagnostic imaging
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Spinal Cord Neoplasms / surgery*
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Spinal Fusion
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Spinal Stenosis / surgery
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Surgery, Computer-Assisted
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Thoracic Vertebrae
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Ultrasonography, Interventional