[Curative effect of ozone hydrotherapy for pemphigus]

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28;43(2):152-156. doi: 10.11817/j.issn.1672-7347.2018.02.008.
[Article in Chinese]


To determine clinical curative effects of ozone therapy for pemphigus vulgaris. Methods: Ozone hydrotherapy was used as an aid treatment for 32 patients with pemphigus vulgaris. The hydropathic compression of potassium permanganate solution for 34 patients with pemphigus vulgaris served as a control. The main treatment for both groups were glucocorticoids and immune inhibitors. The lesions of patients, bacterial infection, usage of antibiotics, patient's satisfaction, and clinical curative effect were evaluated in the 2 groups. Results: There was no significant difference in the curative effect and the average length of staying at hospital between the 2 groups (P>0.05). But rate for the usage of antibiotics was significantly reduced in the group of ozone hydrotherapy (P=0.039). The patients were more satisfied in using ozone hydrotherapy than the potassium permanganate solution after 7-day therapy (P>0.05). Conclusion: Ozone hydrotherapy is a safe and effective aid method for pemphigus vulgaris. It can reduce the usage of antibiotics.


MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Case-Control Studies
  • Dermatologic Agents / therapeutic use*
  • Glucocorticoids
  • Humans
  • Hydrotherapy / methods*
  • Length of Stay
  • Ozone / therapeutic use*
  • Pemphigus / therapy*
  • Potassium Permanganate / therapeutic use
  • Treatment Outcome


  • Anti-Bacterial Agents
  • Dermatologic Agents
  • Glucocorticoids
  • Potassium Permanganate
  • Ozone