Serologic identification of the murine T3 homologue by cross-reactive xenogeneic anti-human T3 antisera

Mol Immunol. 1987 Feb;24(2):201-4. doi: 10.1016/0161-5890(87)90093-9.

Abstract

Hamsters immunized with affinity purified human T3 produced antibodies capable of immunoprecipitating the human T3/T cell receptor complex. In addition, these antisera detected similar molecular complexes by immunoprecipitation of surface labeled murine T cells, and thus contain antibodies which detect a cross-reactive epitope(s) on human and mouse T3.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antigens, Surface / analysis*
  • CD3 Complex
  • Cell Line
  • Cricetinae
  • Cricetulus
  • Cross Reactions
  • Electrophoresis, Polyacrylamide Gel
  • Humans
  • Immune Sera / immunology
  • Mice
  • Rabbits
  • Rats
  • Rats, Inbred Strains
  • T-Lymphocytes / immunology*

Substances

  • Antigens, Surface
  • CD3 Complex
  • Immune Sera