When Antibiotics Turn Toxic

Nature. 2018 Mar 22;555(7697):431-433. doi: 10.1038/d41586-018-03267-5.

MeSH terms

  • Aminoglycosides / adverse effects
  • Animals
  • Anti-Bacterial Agents / adverse effects*
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Ciprofloxacin / pharmacology
  • Ciprofloxacin / therapeutic use
  • Female
  • Fluoroquinolones / adverse effects*
  • Fluoroquinolones / metabolism
  • Genetic Testing
  • Humans
  • Inactivation, Metabolic / genetics
  • Levofloxacin / adverse effects
  • Male
  • Mice
  • Mitochondria / drug effects
  • Mitochondria / pathology
  • Naphthyridines / adverse effects
  • Ofloxacin / adverse effects
  • Oxidative Stress / drug effects
  • Syndrome
  • Topoisomerase II Inhibitors / adverse effects
  • United States
  • United States Food and Drug Administration

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Antioxidants
  • Fluoroquinolones
  • Naphthyridines
  • Topoisomerase II Inhibitors
  • Ciprofloxacin
  • Levofloxacin
  • trovafloxacin
  • Ofloxacin