How an intrinsic ligand tunes the activity of a potassium channel

J Gen Physiol. 2018 Apr 2;150(4):517-520. doi: 10.1085/jgp.201812011. Epub 2018 Mar 22.

Authors

Keith K Khoo¹, Stephan A Pless²

Affiliations

¹ Department of Drug Design and Pharmacology, Center for Biopharmaceuticals, University of Copenhagen, Copenhagen, Denmark.
² Department of Drug Design and Pharmacology, Center for Biopharmaceuticals, University of Copenhagen, Copenhagen, Denmark stephan.pless@sund.ku.dk.

Abstract

Khoo and Pless examine new work that provides mechanistic insight into the role of the intrinsic ligand in KCNH ion channels.

Publication types

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MeSH terms

Ligands
Potassium Channel Blockers
Potassium Channels, Inwardly Rectifying*

Substances

Ligands
Potassium Channel Blockers
Potassium Channels, Inwardly Rectifying