Stoned-A Syndrome of D-Lactic Acidosis and Urolithiasis

Nutr Clin Pract. 2018 Dec;33(6):897-901. doi: 10.1002/ncp.10063. Epub 2018 Mar 23.


Short bowel syndrome (SBS) can lead to many complications related to the condition and its therapy. We describe 2 children with SBS who we believe are the second and third patients documented to have experienced both D-lactic acidosis and urolithiasis. We review aspects of these SBS complications and recent findings on the microbiome of patients with SBS that may predispose to these complications.

Keywords: D-lactate; D-lactic acidosis; dysbiosis; hyperoxaluria; hypocitraturia; lactobacillus; pediatrics; probiotics; short bowel syndrome; small bowel bacterial overgrowth; urolithiasis.

Publication types

  • Case Reports

MeSH terms

  • Acidosis, Lactic / etiology*
  • Adolescent
  • Dysbiosis / etiology*
  • Feces
  • Female
  • Gastrointestinal Microbiome*
  • Humans
  • Infant
  • Lactic Acid / metabolism
  • Lactobacillus / growth & development
  • Lactobacillus / metabolism
  • Male
  • Short Bowel Syndrome / complications*
  • Syndrome
  • Urolithiasis / etiology*


  • Lactic Acid