Management of high-risk breast lesions found on mammogram or ultrasound: the value of contrast-enhanced MRI to exclude malignancy

Clin Imaging. 2018 May-Jun:49:174-180. doi: 10.1016/j.clinimag.2018.03.011. Epub 2018 Mar 13.

Abstract

Purpose: To evaluate the performance of magnetic resonance imaging (MRI) to exclude malignancy in biopsy-proven high-risk breast lesions prior to surgical excision.

Material and methods: Breast MRIs performed after a core needle biopsy (CNB) yielding high-risk pathology were evaluated for the presence of suspicious enhancement. The diagnostic performance of MRI to exclude malignancy was calculated.

Results: The average reader sensitivity, specificity, negative predictive value, positive predictive value and accuracy of MRI were 92%, 51%, 98%, 22% and 56%, respectively.

Conclusion: Lack of enhancement on MRI at the site of a high-risk lesion was useful for excluding malignancy.

Keywords: Breast MRI; Breast cancer; Core needle biopsy; High-risk lesions; Upgrade.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • Biopsy, Large-Core Needle
  • Breast / pathology*
  • Breast / surgery
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Contrast Media*
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Mammography / methods
  • Middle Aged
  • Retrospective Studies
  • Sensitivity and Specificity
  • Ultrasonography / methods

Substances

  • Contrast Media