Recent Developments in Sex-Related Differences in Presentation, Prognosis, and Management of Coronary Artery Disease

Can J Cardiol. 2018 Apr;34(4):390-399. doi: 10.1016/j.cjca.2018.01.007. Epub 2018 Jan 16.

Abstract

Coronary artery disease (CAD) is the most prevalent type of heart disease among women and men. Sex-related differences in the presentation, prognosis, and management of patients with CAD has been increasingly studied. Compared with men, women are more likely to present with multiple comorbidities, have a higher prevalence of psychological risk factors, and present with atypical symptoms. These factors, along with delays in seeking medical attention, might contribute to sex-related treatment differences in women with stable angina and acute coronary syndrome. This review article highlights recent evidence examining sex-related differences in stable CAD patients with obstructive CAD, nonobstructive CAD, as well as myocardial infarction.

Publication types

  • Review

MeSH terms

  • Coronary Artery Disease* / diagnosis
  • Coronary Artery Disease* / physiopathology
  • Coronary Artery Disease* / therapy
  • Female
  • Humans
  • Male
  • Patient Care Management
  • Prevalence
  • Prognosis
  • Risk Factors
  • Sex Factors