Usefulness of a pleuroperitoneal shunt for treatment of refractory pleural effusion in a patient receiving maintenance hemodialysis

CEN Case Rep. 2018 Nov;7(2):189-194. doi: 10.1007/s13730-018-0323-4. Epub 2018 Mar 23.


Refractory pleural effusion can be a life-threatening complication in patients receiving maintenance hemodialysis. We report successful treatment of refractory pleural effusion using a Denver® pleuroperitoneal shunt in one such patient. A 54-year-old Japanese man, who had previously undergone left nephrectomy, was admitted urgently to our department because of a high C-reactive protein (CRP) level, right pleural effusion, and right renal abscess. Because antibiotics proved ineffective and his general state was deteriorating, he underwent emergency insertion of a thoracic drainage tube and nephrectomy, and hemodialysis was started. Although his general state improved slowly thereafter, the pleural effusion, which was unilateral and transudative, remained refractory and therefore he needed to be on oxygenation. To control the massive pleural effusion, a pleuroperitoneal shunt was inserted. Thereafter, his respiratory condition became stable without oxygenation and he was discharged. His general condition has since been well. Although pleural effusion is a common complication of maintenance hemodialysis, few reports have documented the use of pleuroperitoneal shunt to control refractory pleural effusion. Pleuroperitoneal shunt has been advocated as an effective and low-morbidity treatment for refractory pleural effusion, and its use for some patients with recurrent pleural effusion has also been reported, without any severe complications. In the present case, pleuroperitoneal shunt improved the patient's quality of life sufficiently to allow him to be discharged home without oxygenation. Pleuroperitoneal shunt should be considered a useful treatment option for hemodialysis patients with refractory pleural effusion.

Keywords: Hemodialysis; Pleuroperitoneal shunt; Refractory pleural effusion.

Publication types

  • Case Reports

MeSH terms

  • C-Reactive Protein / analysis
  • Chest Tubes / standards
  • Drainage / instrumentation*
  • Exudates and Transudates / chemistry
  • Humans
  • Kidney / microbiology*
  • Kidney / pathology
  • Kidney / surgery
  • Male
  • Middle Aged
  • Nephrectomy / adverse effects
  • Nephrectomy / methods
  • Oxygen Inhalation Therapy / methods
  • Patient Discharge
  • Peritoneal Cavity / surgery*
  • Pleural Effusion / diagnostic imaging
  • Pleural Effusion / surgery*
  • Pleural Effusion / therapy
  • Renal Dialysis / adverse effects*
  • Treatment Outcome


  • C-Reactive Protein