Retinal toxicity due to canthaxanthin. Case series

Arch Soc Esp Oftalmol (Engl Ed). 2018 Aug;93(8):411-415. doi: 10.1016/j.oftal.2018.01.011. Epub 2018 Mar 21.
[Article in English, Spanish]

Abstract

Introduction: Canthaxanthin is a chemical product used to tan the skin. Its most frequent adverse effect is canthaxanthin retinopathy.

Purpose/ methods: Report, case series.

Results: Two female patients, one 42 years-old and the other 72 years-old, with signs of retinopathy due to canthaxanthin. Complete ophthalmology examinations were carried out. The peripheral fovea birefringent deposits with internal retinal involvement were studied using multimodal imaging.

Conclusion: Canthaxanthin retinopathy is rare. Multimodal imaging may provide important data for the differential diagnosis of crystalline retinopathy.

Keywords: Cantaxantina; Canthaxanthin; Retinopathy; Retinopatía; Toxicidad; Toxicity.

MeSH terms

  • Adult
  • Aged
  • Antioxidants / adverse effects*
  • Birefringence
  • Canthaxanthin / adverse effects*
  • Cosmetics / adverse effects*
  • Crystallization
  • Female
  • Humans
  • Optical Imaging
  • Retinal Diseases / chemically induced*
  • Retinal Diseases / diagnostic imaging
  • Slit Lamp Microscopy
  • Tomography, Optical Coherence

Substances

  • Antioxidants
  • Cosmetics
  • Canthaxanthin