Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Jun 9;391(10137):2356-2367.
doi: 10.1016/S0140-6736(18)30480-X. Epub 2018 Mar 21.

What low back pain is and why we need to pay attention

Collaborators, Affiliations
Free article
Review

What low back pain is and why we need to pay attention

Jan Hartvigsen et al. Lancet. .
Free article

Abstract

Low back pain is a very common symptom. It occurs in high-income, middle-income, and low-income countries and all age groups from children to the elderly population. Globally, years lived with disability caused by low back pain increased by 54% between 1990 and 2015, mainly because of population increase and ageing, with the biggest increase seen in low-income and middle-income countries. Low back pain is now the leading cause of disability worldwide. For nearly all people with low back pain, it is not possible to identify a specific nociceptive cause. Only a small proportion of people have a well understood pathological cause-eg, a vertebral fracture, malignancy, or infection. People with physically demanding jobs, physical and mental comorbidities, smokers, and obese individuals are at greatest risk of reporting low back pain. Disabling low back pain is over-represented among people with low socioeconomic status. Most people with new episodes of low back pain recover quickly; however, recurrence is common and in a small proportion of people, low back pain becomes persistent and disabling. Initial high pain intensity, psychological distress, and accompanying pain at multiple body sites increases the risk of persistent disabling low back pain. Increasing evidence shows that central pain-modulating mechanisms and pain cognitions have important roles in the development of persistent disabling low back pain. Cost, health-care use, and disability from low back pain vary substantially between countries and are influenced by local culture and social systems, as well as by beliefs about cause and effect. Disability and costs attributed to low back pain are projected to increase in coming decades, in particular in low-income and middle-income countries, where health and other systems are often fragile and not equipped to cope with this growing burden. Intensified research efforts and global initiatives are clearly needed to address the burden of low back pain as a public health problem.

PubMed Disclaimer

Comment in

  • Low back pain.
    Paraskevas KI. Paraskevas KI. Lancet. 2018 Dec 15;392(10164):2547-2548. doi: 10.1016/S0140-6736(18)32182-2. Lancet. 2018. PMID: 30563635 No abstract available.
  • Low back pain.
    Bailey DM, Byfield D, du Rose A, Corkill R. Bailey DM, et al. Lancet. 2018 Dec 15;392(10164):2548. doi: 10.1016/S0140-6736(18)32210-4. Lancet. 2018. PMID: 30563637 No abstract available.
  • Lessons from The Lancet Low Back Pain Series media strategy.
    O'Keeffe M, Maher CG, Rozbroj T, Schoene M, Buchbinder R. O'Keeffe M, et al. Lancet. 2020 Nov 14;396(10262):1560-1561. doi: 10.1016/S0140-6736(20)32325-4. Lancet. 2020. PMID: 33189175 No abstract available.

Similar articles

  • Tackling low back pain in Brazil: a wake-up call.
    Ferreira G, Costa LM, Stein A, Hartvigsen J, Buchbinder R, Maher CG. Ferreira G, et al. Braz J Phys Ther. 2019 May-Jun;23(3):189-195. doi: 10.1016/j.bjpt.2018.10.001. Epub 2018 Oct 13. Braz J Phys Ther. 2019. PMID: 30337255 Free PMC article. Review.
  • Low back pain: a call for action.
    Buchbinder R, van Tulder M, Öberg B, Costa LM, Woolf A, Schoene M, Croft P; Lancet Low Back Pain Series Working Group. Buchbinder R, et al. Lancet. 2018 Jun 9;391(10137):2384-2388. doi: 10.1016/S0140-6736(18)30488-4. Epub 2018 Mar 21. Lancet. 2018. PMID: 29573871
  • Risk Factors and Disability Associated with Low Back Pain in Older Adults in Low- and Middle-Income Countries. Results from the WHO Study on Global AGEing and Adult Health (SAGE).
    Stewart Williams J, Ng N, Peltzer K, Yawson A, Biritwum R, Maximova T, Wu F, Arokiasamy P, Kowal P, Chatterji S. Stewart Williams J, et al. PLoS One. 2015 Jun 4;10(6):e0127880. doi: 10.1371/journal.pone.0127880. eCollection 2015. PLoS One. 2015. PMID: 26042785 Free PMC article.
  • Tuberculosis.
    Bloom BR, Atun R, Cohen T, Dye C, Fraser H, Gomez GB, Knight G, Murray M, Nardell E, Rubin E, Salomon J, Vassall A, Volchenkov G, White R, Wilson D, Yadav P. Bloom BR, et al. In: Holmes KK, Bertozzi S, Bloom BR, Jha P, editors. Major Infectious Diseases. 3rd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2017 Nov 3. Chapter 11. In: Holmes KK, Bertozzi S, Bloom BR, Jha P, editors. Major Infectious Diseases. 3rd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2017 Nov 3. Chapter 11. PMID: 30212088 Free Books & Documents. Review.
  • Placing the global burden of low back pain in context.
    Buchbinder R, Blyth FM, March LM, Brooks P, Woolf AD, Hoy DG. Buchbinder R, et al. Best Pract Res Clin Rheumatol. 2013 Oct;27(5):575-89. doi: 10.1016/j.berh.2013.10.007. Epub 2013 Oct 12. Best Pract Res Clin Rheumatol. 2013. PMID: 24315140 Review.

Cited by