Ultrasound and the Evaluation of Pediatric Thyroid Malignancy: Current Recommendations for Diagnosis and Follow-up

J Ultrasound Med. 2018 Oct;37(10):2311-2324. doi: 10.1002/jum.14593. Epub 2018 Mar 25.

Abstract

Ultrasound (US) plays a critical role in the evaluation, treatment, screening, and surveillance of thyroid malignancy in pediatric patients. This review aims to summarize recent advances in this topic. Improvements in imaging technology have amplified the advantage of US and US-guided fine-needle aspiration biopsy for thyroid nodule evaluation, cancer diagnosis, and surgical planning. Ultrasound has a definitive screening role for early cancer detection in high-risk patients, including those with a history of radiation exposure from childhood treatments, environmental radiation disasters, or hereditary/familial cancer syndromes. Finally, US is a key component of lifelong surveillance for recurrence among pediatric thyroid cancer survivors.

Keywords: American Thyroid Association guidelines; head and neck; lymph node surveillance; pediatrics; thyroid cancer; thyroid/parathyroid; thyroidectomy; ultrasound.

Publication types

  • Review

MeSH terms

  • Biopsy, Fine-Needle
  • Child
  • Humans
  • Image-Guided Biopsy
  • Thyroid Gland / diagnostic imaging*
  • Thyroid Gland / pathology*
  • Thyroid Neoplasms / diagnostic imaging*
  • Thyroid Neoplasms / pathology*
  • Thyroid Nodule / diagnostic imaging
  • Thyroid Nodule / pathology
  • Ultrasonography / methods*
  • Ultrasonography, Interventional