[Ocular tuberculosis : A case series]

Rev Med Interne. 2018 May;39(5):326-331. doi: 10.1016/j.revmed.2018.02.014. Epub 2018 Mar 23.
[Article in French]

Abstract

Objectives: Ocular tuberculosis is a rare form of extra pulmonary tuberculosis. It represents 1-2% of all clinical forms. The aim of this work was to focus on diagnostic and therapeutic characteristics of ocular tuberculosis.

Methods: We report a case series of 14 patients with ocular tuberculosis seen in an infectious diseases department between 2006 and 2015. The diagnosis was retained on clinical data and a positive tuberculin skin test or interferon-gamma release assay.

Results: The patient's mean age was 40.7±9years. The most common clinical presentation was uveitis (11 patients and 16 eyes). An extra ocular involvement was associated in three patients. The mean duration of antitubercular therapy was 10±2.5 months. Corticosteroid therapy was associated in 11 cases. The outcome was favorable in all cases. Two patients had maintained visual sequelae.

Conclusion: Ocular tuberculosis is a rare disease but still remains a diagnostic problem. It should be considered in case of any chronic ocular symptoms, especially in endemic countries. Early management can improve the visual prognosis.

Keywords: Antitubercularagents; Antituberculeux; Mycobacterium tuberculosis; Mycobacteriumtuberculosis; Retinalvasculitis; Tuberculose; Tuberculosis; Uveitis; Uvéite; Vascularite rétinienne.

MeSH terms

  • Adult
  • Angiography
  • Antitubercular Agents / therapeutic use*
  • Eye / microbiology
  • Eye / pathology
  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium tuberculosis
  • Prognosis
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Tuberculosis, Ocular / diagnosis*
  • Tuberculosis, Ocular / drug therapy

Substances

  • Antitubercular Agents
  • Glucocorticoids