Immunopathological changes after multiple spider bites

Contact Dermatitis. 1987 Aug;17(2):65-8. doi: 10.1111/j.1600-0536.1987.tb02662.x.


Utilizing a panel of immune complex assays, antigen-antibody complex formation in a 29-year-old man shortly after a spider bite was documented. The clinical picture and laboratory parameters were consistent with a serum sickness reaction. Immune hyperactivity was evidenced by a detectable autoimmune serological response. This constellation of findings may be a common attendant to arthropod envenomation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Antinuclear / analysis
  • Antigen-Antibody Complex / analysis
  • Complement C4 / analysis
  • Humans
  • Immune Complex Diseases / etiology*
  • Male
  • Serologic Tests
  • Serum Sickness / etiology
  • Spider Bites / immunology*


  • Antibodies, Antinuclear
  • Antigen-Antibody Complex
  • Complement C4