Wound healing applications of biogenic colloidal silver and gold nanoparticles: recent trends and future prospects

Appl Microbiol Biotechnol. 2018 May;102(10):4305-4318. doi: 10.1007/s00253-018-8939-z. Epub 2018 Mar 27.


Nanotechnology has emerged as a prominent scientific discipline in the technological revolution of this millennium. The scientific community has focused on the green synthesis of metal nanoparticles as compared to physical and chemical methods due to its eco-friendly nature and high efficacy. Medicinal plants have been proven as the paramount source of various phytochemicals that can be used for the biogenic synthesis of colloidal silver and gold nanoparticles as compared to other living organisms, e.g., microbes and fungi. According to various scientific reports, the biogenic nanoparticles have shown promising potential as wound healing agents. However, not a single broad review article was present that demonstrates the wound healing application of biogenic silver and gold nanoparticles. Foreseeing the overall literature published, we for the first time intended to discuss the current trends in wound healing via biogenic silver and gold nanoparticles. Furthermore, light has been shed on the mechanistic aspects of wound healing along with futuristic discussion on the faith of biogenic silver and gold nanoparticles as potential wound healing agents.

Keywords: Gold nanoparticles; Green synthesis; Nanomedicine; Phytonanotechnology; Silver nanoparticles; Wound healing.

Publication types

  • Review

MeSH terms

  • Gold / therapeutic use*
  • Humans
  • Metal Nanoparticles / therapeutic use*
  • Silver / therapeutic use*
  • Wound Healing*


  • colloidal silver
  • Silver
  • Gold