Aminochrome Induces Irreversible Mitochondrial Dysfunction by Inducing Autophagy Dysfunction in Parkinson's Disease

Juan Segura-Aguilar; Sandro Huenchuguala

doi:10.3389/fnins.2018.00106

Aminochrome Induces Irreversible Mitochondrial Dysfunction by Inducing Autophagy Dysfunction in Parkinson's Disease

Front Neurosci. 2018 Mar 13:12:106. doi: 10.3389/fnins.2018.00106. eCollection 2018.

Authors

Juan Segura-Aguilar¹, Sandro Huenchuguala²

Affiliations

¹ Molecular and Clinical Pharmacology, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), University of Chile, Santiago, Chile.
² Departamento de Ciencias Biológicas y Químicas, Facultad de Ciencia, Universidad San Sebastián, Puerto Montt, Chile.

No abstract available

Keywords: aminochrome; autophagy dysfunction; dopamine; lysosomal dysfunction; mitochondrial dysfunction; neurodegeneration; neuromelanin; parkinson's disease.