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Review
. 2018 Feb 1;9:35-41.
doi: 10.1016/j.ctro.2018.01.006. eCollection 2018 Feb.

Relative Biological Effectiveness in Proton Beam Therapy - Current Knowledge and Future Challenges

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Free PMC article
Review

Relative Biological Effectiveness in Proton Beam Therapy - Current Knowledge and Future Challenges

Armin Lühr et al. Clin Transl Radiat Oncol. .
Free PMC article

Abstract

No abstract available

Keywords: Clinical side-effects; Dose recalculation; In vitro and in vivo models; MRI; RBE; Relative biological effectiveness.

Figures

Fig. 1
Fig. 1
Proton treatment plan for a primary brain tumor patient with a prescribed dose of 60 Gy(RBE) to the CTV. (A) Absorbed physical dose Dphys; (B) LET distribution; (C) variable RBE distribution based on measured in vitro RBE data , which depend on dose and LET; (D) difference in RBE-weighted dose: Dphys × RBE − Dphys × 1.1. Courtesy of Jan Eulitz and Christian Hahn.

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