Psychotropic Medication Use Among Adults With Schizophrenia and Schizoaffective Disorder in the United States

Psychiatr Serv. 2018 May 1;69(5):605-608. doi: 10.1176/appi.ps.201700356. Epub 2018 Apr 2.

Abstract

Objective: The authors examined the use of different classes of psychotropic medication in outpatient treatment of schizophrenia and schizoaffective disorder.

Methods: Data from the United States Medicaid program were used to examine psychotropic medication use in a cohort of patients who had a diagnosis of schizophrenia or schizoaffective disorder in the calendar year 2010.

Results: The cohort of Medicaid recipients who filled one or more prescriptions for a psychotropic medication in 2010 included 116,249 patients classified as having schizophrenia and 84,537 classified as having schizoaffective disorder. During 2010, 86.1% of patients with schizoaffective disorder and 70.1% with schizophrenia were treated with two or more different classes of psychotropic.

Conclusions: Psychotropic medications other than antipsychotics were commonly prescribed for individuals with a diagnosis of schizophrenia or schizoaffective disorder. Their widespread use and uncertainty about their net benefits signal a need for research on their efficacy, safety, and appropriate use in these conditions.

Keywords: Psychopharmacology/general; Schizoaffective disorders; Schizophrenia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Drug Prescriptions / statistics & numerical data*
  • Drug Utilization / statistics & numerical data*
  • Female
  • Humans
  • Male
  • Medicaid / statistics & numerical data*
  • Middle Aged
  • Psychotic Disorders / drug therapy*
  • Psychotropic Drugs / therapeutic use*
  • Retrospective Studies
  • Schizophrenia / drug therapy*
  • United States

Substances

  • Psychotropic Drugs