Histoplasmosis Myocarditis in an Immunocompetent Host After a Recreational Mud Run

Pediatrics. 2018 Apr;141(Suppl 5):S462-S465. doi: 10.1542/peds.2017-1074.


Mud runs are an increasingly popular recreational fitness activity across the United States, combining a running race through an obstacle course with submersion in mud. Recent reports estimate 4 million people have participated in these types of events over the last 5 years. We describe an atypical case of myocarditis and multiorgan failure from disseminated histoplasmosis in a previously healthy pediatric patient, likely acquired during participation in a mud run. Although cases of histoplasmosis-associated endocarditis and pericarditis have been reported in the literature, cases of histoplasmosis myocarditis are rare.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Endemic Diseases
  • Female
  • Histoplasmosis / complications
  • Histoplasmosis / diagnosis*
  • Histoplasmosis / immunology
  • Humans
  • Immunocompetence
  • Multiple Organ Failure / microbiology
  • Myocarditis / complications
  • Myocarditis / diagnosis*
  • Myocarditis / immunology
  • Myocarditis / microbiology*
  • North Carolina
  • Running*
  • Soil Microbiology*