Effect of vitamin D supplementation on anthropometric indices among overweight and obese women: A double blind randomized controlled clinical trial

Abstract

Aims: The aim of this study was to investigate effect of vitamin D supplementation on anthropometric indices among women with overweight and obesity.

Methods: This double blind randomize clinical trial was conducted on 66 overweight and obese women. Those in intervention group received oral supplement of vitamin D 50,000 IU (1250 mcg) per 25 day and in control group participants received placebo for 3 months. Anthropometric indices were measured before and after 3 months intervention. Before the intervention a 24-h dietary recall (3 days) were used to assess dietary intake of individuals. Independent t test and multivariate repeated measure were used to data analysis.

Results: The mean difference of anthropometric indices, serum calcium, 25 (OH) D₃ and serum PTH between the intervention and control groups were significant (P < 0/05). However, no significant differences in serum phosphorus between the intervention and control groups were seen.

Conclusion: Supplementation with vitamin D 50 μg for each day for 3 months resulted in a significant reduction in anthropometric indices in women with obesity and overweight with normal primary 25(OH) D₃ serum levels.

Keywords: Anthropometric indices; Obesity; Overweight; Vitamin D; Waist circumferences; Weight.