Effect of vitamin D supplementation on anthropometric indices among overweight and obese women: A double blind randomized controlled clinical trial

Diabetes Metab Syndr. 2018 Jul;12(4):537-541. doi: 10.1016/j.dsx.2018.03.022. Epub 2018 Mar 27.


Aims: The aim of this study was to investigate effect of vitamin D supplementation on anthropometric indices among women with overweight and obesity.

Methods: This double blind randomize clinical trial was conducted on 66 overweight and obese women. Those in intervention group received oral supplement of vitamin D 50,000 IU (1250 mcg) per 25 day and in control group participants received placebo for 3 months. Anthropometric indices were measured before and after 3 months intervention. Before the intervention a 24-h dietary recall (3 days) were used to assess dietary intake of individuals. Independent t test and multivariate repeated measure were used to data analysis.

Results: The mean difference of anthropometric indices, serum calcium, 25 (OH) D3 and serum PTH between the intervention and control groups were significant (P < 0/05). However, no significant differences in serum phosphorus between the intervention and control groups were seen.

Conclusion: Supplementation with vitamin D 50 μg for each day for 3 months resulted in a significant reduction in anthropometric indices in women with obesity and overweight with normal primary 25(OH) D3 serum levels.

Keywords: Anthropometric indices; Obesity; Overweight; Vitamin D; Waist circumferences; Weight.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anthropometry*
  • Body Mass Index*
  • Case-Control Studies
  • Dietary Supplements*
  • Double-Blind Method
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Obesity / etiology
  • Obesity / prevention & control*
  • Overweight / etiology
  • Overweight / prevention & control*
  • Prognosis
  • Vitamin D / administration & dosage*
  • Vitamin D Deficiency / complications*
  • Vitamins / administration & dosage
  • Young Adult


  • Vitamins
  • Vitamin D