Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator

Libo Shan; Ping He

doi:10.1016/j.cell.2018.03.045

Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator

Cell. 2018 Apr 5;173(2):286-287. doi: 10.1016/j.cell.2018.03.045.

Authors

Libo Shan¹, Ping He²

Affiliations

¹ Department of Plant Pathology and Microbiology and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, USA. Electronic address: lshan@tamu.edu.
² Department of Biochemistry and Biophysics and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, USA. Electronic address: pinghe@tamu.edu.

PMID: 29625046
DOI: 10.1016/j.cell.2018.03.045

Abstract

The non-protein amino acid pipecolic acid (Pip) is a lysine catabolite involved in plant systemic acquired resistance (SAR). In this issue of Cell, Hartmann et al. (2018) demonstrate that a flavin-dependent monooxygenase converts Pip to N-hydroxypipecolic acid (NHP), which functions as a critical metabolic regulator of SAR in Arabidopsis.

Publication types

Comment

MeSH terms

Arabidopsis
Arabidopsis Proteins*
Flavins
Mixed Function Oxygenases
Pipecolic Acids*
Pseudomonas syringae

Substances

Arabidopsis Proteins
Flavins
Pipecolic Acids
Mixed Function Oxygenases

Grants and funding

R01 GM097247/GM/NIGMS NIH HHS/United States