Current guidelines for prostate cancer screening: A systematic review and minimal core proposal

Rev Assoc Med Bras (1992). 2018 Mar;64(3):290-296. doi: 10.1590/1806-9282.64.03.290.


Objective: Considering the importance of screening for prostate cancer, the possibility of damage resulting from indiscriminate screening and the difficulty of disclosure and adherence to the main guidelines on the subject, we aimed to identify current guidelines, look for common approaches and establish a core of conducts.

Method: Systematic review of the literature on screening practice guidelines for prostate cancer searching the databases PubMed, Lilacs and Google Scholar and active search in the sites of several national health entities.

Results: Twelve (12) guidelines were selected, whose analysis resulted in the identification of six common points of conduct, with the following minimum core of recommendations: (1) screening indication or not: must be individualized, and preceded by an informed decision; (2) tests used: PSA with or without rectal digital examination; (3) age at which initiate testing in men in general risk: 50-55 years; (4) age at which to initiate testing in men at increased risk: 40-45 years; (5) the interval between screening: annual or biennial; and (6) age at which to discontinue testing: 70 years-old or life expectancy less than 10 years.

Conclusion: Although there are differences between them, it was possible to establish a minimum core of conducts that may be useful in the daily practice of the physician.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Age of Onset
  • Early Detection of Cancer / standards*
  • Humans
  • Male
  • Mass Screening / standards*
  • Practice Guidelines as Topic*
  • Prostate-Specific Antigen / standards
  • Prostatic Neoplasms / diagnosis*


  • Prostate-Specific Antigen