My winding path toward a career in science was awkward, like an adolescent finding an identity. It did not follow a classic course; it had many interruptions, complications, and challenges. It also involved a bit of luck and extremely supportive colleagues, mentors, and family, including my husband, children, and in-laws. I was inspired to tell my story here because I met a young woman interviewing in 2018 for graduate school who is growing up with the same complicated family expectations, social challenges, love for science, and desire to be a scientist as I had four decades ago. Her future is uncertain, because her chosen academic path is not encouraged by those around her. We, as a society, must find ways to encourage, promote, enable, and give strength to those who want to follow their dreams, despite facing many challenges in their lives. Here are some things I learned on my career path that I hope might be helpful for others.
Keywords: AMPylation; YopJ; acetylation; enzyme mechanism; microbiology; post-translational modification (PTM); signal transduction; type III secretion system (T3SS).
© 2018 Orth.