The characterization of surgical smoke from various tissues and its implications for occupational safety

PLoS One. 2018 Apr 12;13(4):e0195274. doi: 10.1371/journal.pone.0195274. eCollection 2018.

Abstract

Electrosurgery produces surgical smoke. Different tissues produce different quantities and types of smoke, so we studied the particle characteristics of this surgical smoke in order to analyze the implications for the occupational health of the operation room personnel. We estimated the deposition of particulate matter (PM) from surgical smoke on the respiratory tract of operation room personnel using clinically relevant tissues from Finnish landrace porcine tissues including skeletal muscle, liver, subcutaneous fat, renal pelvis, renal cortex, lung, bronchus, cerebral gray and white matter, and skin. In order to standardize the electrosurgical cuts and smoke concentrations, we built a customized computer-controlled platform. The smoke particles were analyzed with an electrical low pressure impactor (ELPI), which measures the concentration and aerodynamic size distribution of particles with a diameter between 7 nm and 10 μm. There were significant differences in the mass concentration and size distribution of the surgical smoke particles depending on the electrocauterized tissue. Of the various tissues tested, liver yielded the highest number of particles. In order to better estimate the health hazard, we propose that the tissues can be divided into three distinct classes according to their surgical smoke production: 1) high-PM tissue for liver; 2) medium-PM tissues for renal cortex, renal pelvis, and skeletal muscle; and 3) low-PM tissues for skin, gray matter, white matter, bronchus, and subcutaneous fat.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Electricity*
  • Occupational Exposure / adverse effects*
  • Occupational Exposure / analysis*
  • Occupational Health
  • Safety*
  • Smoke / adverse effects*
  • Smoke / analysis*
  • Surgical Procedures, Operative / adverse effects*
  • Swine

Substances

  • Smoke

Grant support

This study was supported by grants from following foundations: Finnish Foundation for Technology Promotion (TES) to M.K., Tampereen Tuberkuloosisäätiö (Tampere Tuberculosis Foundation), Emil Aaltonen foundation, and Pirkanmaan sairaanhoitopiiri (PSHP) grants 9s045, 151B03, 9T044, 9U042, 150618, and 9V044 to N.O., which were used partially for salaries for authors M.K. and A.K. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section. Olfactomics Ltd did not provide any funding for the study and did not play any role in the study design.