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, 18 (1), 91

The Prevalence and Systemic Risk Factors of Diabetic Macular Edema: A Cross-Sectional Study From Turkey

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The Prevalence and Systemic Risk Factors of Diabetic Macular Edema: A Cross-Sectional Study From Turkey

Durgul Acan et al. BMC Ophthalmol.

Abstract

Background: The aim of this study was to evaluate the prevalence of diabetic macular edema (DME) utilizing optical coherence tomography (OCT), and to clarify the effects of the systemic findings and risk factors on the development of DME.

Methods: This cross-sectional study was conducted in the departments of ophthalmology and endocrinology at the Dokuz Eylul University School of Medicine in Izmir, Turkey. The demographics, type and duration of diabetes mellitus, treatment modality, smoking and alcohol consumption habits, as well as the systemic blood pressure, renal functional tests, hemoglobulin A1c level, serum lipid profile, and 24-h urine albumin level were noted and statistically analyzed. The relationships between the systemic findings and DME were studied.

Results: Four-hundred and thirteen eyes of 413 diabetic patients who were examined between January 2011 and July 2012 were enrolled in this study. The prevalence of DME was 15.3% among the patients. The males exhibited DME significantly more frequently than the females (p = 0.031), and the duration of diabetes was significantly longer in those patients with DME (p < 0.001). Those patients without DME frequently used antihyperlipidemic drugs and had a higher level of high density lipoprotein cholesterol (p = 0.040 and p = 0.046, respectively). The patient's alcohol consumption, nephropathy, neuropathy, previous cataract surgery, severity of diabetic retinopathy, and insulin usage were statistically significant factors with regard to the DME prevalence.

Conclusions: This study demonstrated the prevalence of DME in Turkey by utilizing OCT. The development of DME can be avoided or limited and the response to treatment may be improved by the regulation of the DME risk factors.

Keywords: Diabetic macular edema; Optical coherence tomography; Prevalence.

Conflict of interest statement

Ethics approval and consent to participate

This study was conducted with approval from the Local Ethics Committee of the Dokuz Eylul University (reference number: 572GA). Administrative permission was granted to access the patient database. The patients provided informed consent for the use of their information in this research.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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References

    1. Global report on diabetes. World Health Organization, Geneva. 2016. http://www.who.int/diabetes/global-report/en/.
    1. Diabetes country profiles. World Health Organization, Geneva. 2016. http://www.who.int/diabetes/country-profiles/en/.
    1. Cugati S, Kifley A, Mitchell P, Wang JJ. Temporal trends in the age-specific prevalence of diabetes and diabetic retinopathy in older persons: population-based survey findings. Diabetes Res Clin Pract. 2006;74:301–308. doi: 10.1016/j.diabres.2006.04.002. - DOI - PubMed
    1. Pedro RA, Ramon SA, Marc BB, Juan FB, Isabel MM. Prevalence and relationship between diabetic retinopathy and nephropathy, and its risk factors in the north-east of Spain, a population-based study. Ophthalmic Epidemiol. 2010;17:251–265. doi: 10.3109/09286586.2010.498661. - DOI - PubMed
    1. Bertelsen G, Peto T, Lindekleiv H, Schirmer H, Solbu MD, Toft I, Sjølie AK, Njølstad I. Tromsø eye study: prevalence and risk factors of diabetic retinopathy. Acta Ophthalmol. 2013;91:716–721. doi: 10.1111/j.1755-3768.2012.02542.x. - DOI - PubMed
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