Acoustic analysis of voices of patients with neurologic disease: rationale and preliminary data

Ann Otol Rhinol Laryngol. Mar-Apr 1988;97(2 Pt 1):164-72. doi: 10.1177/000348948809700214.


This paper presents a rationale for acoustic analysis of voices of neurologically diseased patients, and reports preliminary data from patients with myotonic dystrophy, Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis, as well as from individuals at risk for Huntington's disease. Noninvasive acoustic analysis may be of clinical value to the otolaryngologist, neurologist, and speech pathologist for early and differential diagnosis and for documenting disease progression in these various neurologic disorders.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Amyotrophic Lateral Sclerosis / physiopathology
  • Female
  • Humans
  • Huntington Disease / physiopathology
  • Male
  • Middle Aged
  • Myotonic Dystrophy / physiopathology
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / physiopathology*
  • Parkinson Disease / physiopathology
  • Speech Acoustics*
  • Speech*
  • Voice Quality*
  • Voice*