Dopamine D-1 receptor agonist stimulation of prolactin secretion in man

G Fabbrini; A Braun; M M Mouradian; C A Tamminga; T N Chase

doi:10.1007/BF01245709

Dopamine D-1 receptor agonist stimulation of prolactin secretion in man

J Neural Transm. 1988;71(3):159-63. doi: 10.1007/BF01245709.

Authors

G Fabbrini¹, A Braun, M M Mouradian, C A Tamminga, T N Chase

Affiliation

¹ Experimental Therapeutics Branch, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Maryland.

PMID: 2965754
DOI: 10.1007/BF01245709

Abstract

SKF 38393, a selective D-1 dopamine receptor agonist, elevated plasma prolactin levels in eight patients with various neurological disorders. Growth hormone concentrations were unaffected by SKF 38393 administration. The results suggest that D-1 receptors may be involved in the regulation of prolactin secretion.

MeSH terms

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
Benzazepines / administration & dosage*
Dyskinesia, Drug-Induced / blood*
Dyskinesia, Drug-Induced / drug therapy
Female
Growth Hormone / blood
Humans
Huntington Disease / blood*
Huntington Disease / drug therapy
Male
Middle Aged
Parkinson Disease / blood*
Parkinson Disease / drug therapy
Prolactin / metabolism*
Receptors, Dopamine / drug effects
Receptors, Dopamine / physiology*
Receptors, Dopamine D1

Substances

Benzazepines
Receptors, Dopamine
Receptors, Dopamine D1
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
Prolactin
Growth Hormone