A clinical threat in patients with granulomatosis polyangiitis in remission: Subglottic stenosis

Eur J Rheumatol. 2018 Mar;5(1):69-71. doi: 10.5152/eurjrheum.2017.16025. Epub 2017 Apr 11.


Granulomatosis with polyangiitis (GPA) is a systemic necrotizing granulomatous disease that involves small- and medium-sized arteries and affects the main respiratory tracts and kidneys. Upper respiratory tract involvement usually occurs in 90% of patients, who most frequently present with symptoms of chronic sinusitis. Subglottic stenosis (SS) is a rare and severe complication that is usually observed in approximately 15% of patients. Here we present a case of SS in a patient with limited form of GPA during remission.

Keywords: Granulomatosis with polyangiitis; rituximab; subglottic stenosis.