High-Intensity Intermittent Exercise Increases Fat Oxidation Rate and Reduces Postprandial Triglyceride Concentrations

Nutrients. 2018 Apr 16;10(4):492. doi: 10.3390/nu10040492.


(1) Background: This study investigated the effect of acute barehanded whole body high-intensity intermittent exercise (HIIE) and moderate intensity and continuous exercise (MICE) at the same quantity of energy expenditure on postprandial triglyceride (TG) concentrations. (2) Methods: Nine healthy males completed three trials (HIIE, MICE and control (CON)) in a random order separated by at least 14 days. After each intervention, the participants rested for 12 h and consumed a high-fat test meal on the next day. The blood samples and respiratory exchange ratio were observed in the fasted state and for 4 h after consuming the test meal. (3) Results: The HIIE had a significantly higher area under the curve of postprandial fat oxidation rate than MICE (p = 0.027) and CON (p = 0.035) and exhibited significantly lower postprandial TG concentration than the MICE and CON at 2 and 4 h after the test meal. Moreover, the HIIE displayed a higher postprandial TG concentration area under the curve than MICE (p = 0.013) and CON (p = 0.048). (4) Conclusions: The present study concluded that acute barehanded whole body HIIE could significantly lower postprandial TG concentrations. It possibly can induce a rise in the postprandial fat oxidation rate.

Keywords: cardiovascular disease; creatine kinase; energy expenditure; respiratory exchange ratio.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Creatine Kinase / blood
  • Cross-Over Studies
  • Exercise / physiology*
  • Fats / metabolism*
  • Fatty Acids, Nonesterified / blood
  • Glycerol / blood
  • Humans
  • Male
  • Oxidation-Reduction
  • Postprandial Period*
  • Triglycerides / blood*
  • Young Adult


  • Fats
  • Fatty Acids, Nonesterified
  • Triglycerides
  • Creatine Kinase
  • Glycerol