Clinical problems in hemodialysis patients with autosomal dominant polycystic kidney disease

Semin Dial. 2018 May;31(3):268-277. doi: 10.1111/sdi.12696. Epub 2018 Apr 17.

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by massive enlargement of fluid-filled cysts in the kidney. Due to its genetic pattern, the disease differs from other CKD. ADPKD is a multi-system, progressive disorder which is frequently complicated with hypertension, cardiovascular events and cerebrovascular disease. Thus, there are many clinical problems specific to ADPKD. In this article, we reviewed these clinical problems and their management in ADPKD with hemodialysis patients.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / physiopathology
  • Cerebrovascular Disorders / etiology
  • Cerebrovascular Disorders / physiopathology
  • Disease Progression
  • Female
  • Humans
  • Kidney Failure, Chronic / etiology*
  • Kidney Failure, Chronic / physiopathology
  • Kidney Failure, Chronic / therapy*
  • Kidney Transplantation / methods*
  • Male
  • Nephrectomy / methods
  • Polycystic Kidney, Autosomal Dominant / complications*
  • Polycystic Kidney, Autosomal Dominant / diagnosis
  • Polycystic Kidney, Autosomal Dominant / mortality
  • Renal Dialysis / adverse effects*
  • Renal Dialysis / methods
  • Risk Assessment
  • Survival Analysis
  • Treatment Outcome