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Case Reports
. 2018 Apr;23(15):18-00160.
doi: 10.2807/1560-7917.ES.2018.23.15.18-00160.

Case of seasonal reassortant A(H1N2) influenza virus infection, the Netherlands, March 2018

Adam Meijer  1   2 , Corien M Swaan  1 , Martin Voerknecht  3 , Edin Jusic  1 , Sharon van den Brink  1 , Lisa A Wijsman  1 , Bettie Cg Voordouw  1   2 , Gé A Donker  4 , Jacqueline Sleven  5 , Wendelien W Dorigo-Zetsma  6 , Sanela Svraka  6 , Michiel van Boven  1 , Manon R Haverkate  1 , Aura Timen  1 , Jaap T van Dissel  1 , Marion Pg Koopmans  2 , Theo M Bestebroer  2 , Ron Am Fouchier  2
Affiliations
Case Reports

Case of seasonal reassortant A(H1N2) influenza virus infection, the Netherlands, March 2018

Adam Meijer et al. Euro Surveill. 2018 Apr.

Abstract

A seasonal reassortant A(H1N2) influenza virus harbouring genome segments from seasonal influenza viruses A(H1N1)pdm09 (HA and NS) and A(H3N2) (PB2, PB1, PA, NP, NA and M) was identified in March 2018 in a 19-months-old patient with influenza-like illness (ILI) who presented to a general practitioner participating in the routine sentinel surveillance of ILI in the Netherlands. The patient recovered fully. Further epidemiological and virological investigation did not reveal additional cases.

Keywords: emerging or re-emerging diseases; epidemiology; human influenza virus; influenza-like illness - ILI; reassortant; surveillance.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
ILI incidence and number of specimens from patients with ILI collected by sentinel general practitioners in which influenza virus was detected, the Netherlands, 21 March 2018 (n = 395)
Figure 2
Figure 2
Phylogenetic analysis of the influenza A(H1N2) virus haemagglutinin genome segment in the context of a reference influenza virus data seta and recent influenza viruses from the Netherlands
Figure 3
Figure 3
Phylogenetic analysis of the influenza A(H1N2) virus neuraminidase genome segment in the context of a reference influenza virus data seta and recent influenza viruses from the Netherlands
Figure 4
Figure 4
Phylogenetic analysis of the influenza A(H1N2) virus NS genome segment in the context of recent vaccine strains and selected seasonal influenza viruses representative of those circulating in the Netherlands in 2016 and 2017 and in other European countries in January and February 2018a
See this image and copyright information in PMC

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