Clinical Guidelines Update on the Diagnosis and Management of Barrett's Esophagus

Dig Dis Sci. 2018 Aug;63(8):2122-2128. doi: 10.1007/s10620-018-5070-z.


Barrett's esophagus is a condition in which metaplastic columnar epithelium replaces stratified squamous epithelium in the distal esophagus. This condition occurs due to chronic gastroesophageal reflux disease and is a risk factor for the development of esophageal adenocarcinoma. Multiple clinical guidelines have been published around the world in recent years to assist gastroenterologists in the management of these patients and have evolved as new data have become available. While some information such as surveillance technique has not drastically changed, there has been an evolution over the years in diagnostic criteria, screening and endoscopic therapy with a variety of subtle differences among the different guidelines. Herein, we highlight areas of agreement and disagreement on definitions, screening, surveillance, and treatment techniques among these guidelines for the optimal management of Barrett's esophagus patients.

Keywords: Barrett’s esophagus; Dysplasia; Endoscopic mucosal resection; Radiofrequency ablation.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma* / etiology
  • Adenocarcinoma* / pathology
  • Adenocarcinoma* / prevention & control
  • Barrett Esophagus* / complications
  • Barrett Esophagus* / pathology
  • Barrett Esophagus* / therapy
  • Disease Management*
  • Esophageal Neoplasms* / etiology
  • Esophageal Neoplasms* / pathology
  • Esophageal Neoplasms* / prevention & control
  • Humans
  • Practice Guidelines as Topic

Supplementary concepts

  • Adenocarcinoma Of Esophagus