Assessment of the Availability, Cost, and Motivations for Use over Time of the New Psychoactive Substances-Benzodiazepines Diclazepam, Flubromazepam, and Pyrazolam-in the UK

J Med Toxicol. 2018 Jun;14(2):134-143. doi: 10.1007/s13181-018-0659-3. Epub 2018 Apr 18.

Abstract

Introduction: There has been increasing interest in the availability of non-prescription benzodiazepines and their sale as new psychoactive substances. We wanted to determine UK availability from Internet suppliers and motivations for use of three benzodiazepines (diclazepam, flubromazepam, and pyrazolam).

Methods: In November 2014 and March 2016, using the European Monitoring Centre for Drugs and Drug Addiction Snapshot Methodology, Internet search engines ( google.co.uk , uk. yahoo.com and ask.com.uk ) were searched using the terms 'buy diclazepam', 'buy flubromazepam' and 'buy pyrazolam'. Threads from drug-user forums ( bluelight.org , drugs-forum.com , erowid.org , legalhighsforum.com ) were analysed using a general inductive approach. Data were converted into price per gram/pellet to allow cost comparisons and to determine motivations for use.

Results: There was an increase in websites selling these benzodiazepines between 2014 and 2016: diclazepam (49 in 2014 to 55 in 2016), pyrazolam (33 to 35), and flubromazepam (39 to 45). Thirty-eight (63.3%) sites were based in the UK/Europe. Drugs were sold as pellets (49 websites, 81.7%), powder (19, 31.7%), and blotters (1, 1.7%). Pill forms were not available, and one (1.7%) website sold diclazepam/flubromazepam in liquid form. The cost reduced with increasing purchase quantities. Main motivations for use included anxiolysis, management of benzodiazepine withdrawal, sedation/sleep aid, and management of stimulant withdrawal.

Conclusions: These three benzodiazepines are widely available online, most commonly as pellets, and are (mis)used for a number of reasons. This study could be used to support triangulation of data from other sources to inform harm minimisation strategies.

Keywords: Benzodiazepines; Diclazepam; Flubromazepam; New psychoactive substances; Pyrazolam.

MeSH terms

  • Anti-Anxiety Agents
  • Benzodiazepines / economics*
  • Central Nervous System Stimulants
  • Designer Drugs / economics*
  • Diazepam / analogs & derivatives
  • Diazepam / economics
  • Drug Users / psychology*
  • Drug Users / statistics & numerical data*
  • Humans
  • Hypnotics and Sedatives
  • Internet
  • Motivation*
  • Substance Withdrawal Syndrome / drug therapy
  • Substance Withdrawal Syndrome / psychology
  • Substance-Related Disorders / economics*
  • Substance-Related Disorders / psychology*
  • United Kingdom

Substances

  • Anti-Anxiety Agents
  • Central Nervous System Stimulants
  • Designer Drugs
  • Hypnotics and Sedatives
  • 2-chlorodiazepam
  • Benzodiazepines
  • flubromazolam
  • pyrazolam
  • Diazepam