Verrucous Plaque With Unusually Large Candida Blastoconidia: A Unique Clinicopathological Presentation of Systemic Mucocutaneous Candidiasis

Am J Dermatopathol. 2018 Nov;40(11):846-848. doi: 10.1097/DAD.0000000000001153.


Mucocutaneous candidiasis is a common infection affecting both immunocompetent and immunosuppressed individuals. Diversity in the clinical and histopathological presentation of mucocutaneous candidiasis is well known. However, the occurrence of cutaneous verrucous lesions and giant yeast-like structures has been rarely reported. In this article, we describe a case of disseminated mucocutaneous candidiasis in an immunosuppressed patient who presented as a verrucous plaque on the scrotum with giant Candida blastoconidia. This peculiar presentation expands the clinicopathological spectrum of mucocutaneous candidiasis and highlights the wide range of clinical manifestations and great morphologic variability of this common fungal infection.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Candida
  • Candidiasis, Chronic Mucocutaneous / immunology*
  • Candidiasis, Chronic Mucocutaneous / pathology*
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Immunocompromised Host*
  • Male
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Scrotum / microbiology
  • Scrotum / pathology
  • Spores, Fungal